منابع مشابه
Actin gels
Solutions and gels of the filamentous protein F-actin have not only been the subject of numerous recent biophysical studies, but have also proven to be quite fruitful model systems for fundamental polymer science. They are particularly good models of ‘semiflexible’ polymers, because they have an enormous ratio of persistence length to molecular diameter with characteristic mesh sizes of the ord...
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Conflicting experimental results have been reported for the plateau modulus in actin solutions: Analogies are often made with the viscoelastic behaviour of flexible polymers making use of the idea of entanglement as the source of the macroscopic storage modulus. We resolve apparent experimental and theoretical contradictions by pointing out the possibility of two distinct plateau regimes as a f...
متن کاملHydrodynamics of active permeating gels
We develop a hydrodynamic theory of active permeating gels with viscoelasticity in which a polymer network is embedded in a background fluid. This situation is motivated by active processes in the cell cytoskeleton in which motor molecules generate elastic stresses in the network, which can drive permeation flows of the cytosol. Our approach differs from earlier ones by considering the elastic ...
متن کاملMechanical Response of Active Gels
We study a model of an active gel of cross-linked semiflexible filaments with additional active linkers such as myosin II clusters. We show that the coupling of the elasticity of the semiflexible filaments to the mechanical properties of the motors leads to contractile behavior of the gel, in qualitative agreement with experimental observations. The motors, however, soften the zero frequency el...
متن کاملMotility initiation in active gels
Motility initiation in crawling cells requires a symmetry breaking mechanism which transforms a symmetric state into a polarized state. Experiments on keratocytes suggest that polarization is triggered by increased contractility of motor proteins. In this paper we argue that contraction can be responsible not only for the symmetry breaking transition but also for the incipient translocation of ...
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ژورنال
عنوان ژورنال: Communicative & Integrative Biology
سال: 2012
ISSN: 1942-0889
DOI: 10.4161/cib.18286